

88
Criterios de ingreso a Unidad de Pacientes
Críticos (UPC)
- Falla respiratoria inminente.
- Exacerbación grave.
- Requerimiento de FiO
2
mayor a 0,50, después
de 1 h de manejo.
Criterios de alta de Servicio de Urgencia
- Saturación arterial de O
2
igual o mayor a 94%
con aire ambiental, después de 2 h de observa-
ción.
- Ausencia de signos de dificultad respiratoria.
Indicaciones para el hogar
- Evitar factores desencadenantes como conta-
minantes intradomiciliarios (calefacción conta-
minante, tabaquismo), alergenos a los cuales el
niño esté sensibilizado y actividad física entre
otros.
- Si requirió corticoides sistémicos completar a
lo menos 5 días.
- Salbutamol: continuar su uso 2
puffs
cada 4 h
hasta ser controlado por su médico.
- Revisar técnica inhalatoria.
- Plan escrito para manejo precoz en domicilio
de futuras exacerbaciones.
- Control por médico especialista en enfermeda-
des respiratorias, para estudio y seguimiento.
Bibliografía
1.- SEARS M R, GREENE J M, WILLIAMAR, WIECEK
E M, TAYLOR D R, FLANNERY E M, et al. A longi-
tudinal, population-based, cohort study of childhood
asthma followed to adulthood. N Engl J Med 2003; 349:
1414-22.
2.- PHELAN P D, ROBERTSON C F, OLINSKY A. The
Melbourn Asthma Study: 1964-1999. J Allergy Clin
Inmunol 2002; 109: 189-94.
3.- MARTÍNEZ F D. What have we learned from the Tuc-
son Children’s Respiratory Study. Paediatr Respir Rev
2002; 3: 193-7.
4.- TENERO L, TEZZA G, CATTAZZO E , PIACENTINI
G. Wheezing in preschool children. Early Hum Dev
2013; 89 Suppl 3: S13-7.
5.- CASTRO-RODRÍGUEZ J A, HOLBERG C J,
WRIGHT A L, MARTÍNEZ F D. A clinical index to
define risk of asthma in young children with recurrent
wheezing. Am J Respir Crit Care Med 2000; 162: 1403-
6.
6.- MARTÍNEZ F D, WRIGHT A L, TAUSSIG L, HOL-
BERG C J, HALONEN M, MORGAN W J. Asthma
and wheezing in the first six years of life. N Engl J Med
1995; 332: 133-8.
7.- HENDERSON J, GRANELL R, HERON J, SHERRIF
A, SIMPSON A, WOODCOCK A, et al. Associations
of wheezing phenotypes in the first 6 years of life with
atopy, lung function and airway responsiveness in mid-
childhood. Thorax 2008; 63: 974-80.
8.- SONNAPPA S, BASTARDO C M, WADE A, SAGLA-
NI S, MCKENZIE S A, BUSH A, et al. Symptom-
pattern phenotype and pulmonary function in preschool
wheezers. J Allergy Clin Immunol 2010; 126: 519-26.
9.- BRAND P, BARALDI E, BISGAARD, BONER A,
CASTRO-RODRÍGUEZ J A, CUSTOVIC A, et al. De-
finition assessment and treatment of wheezing disorders
in preschool children and evidence based approach. Eur
Resp J 2008; 32: 1096-110.
10.- BRAND P, CAUDRI D, EBER E, GAILLARD E A,
GARCÍA-MARCOS L, HEDLIN G, et al. Classification
and pharmacological treatment of preschool wheezing:
changes since 2008. Eur Respir J 2014; 43: 1172-7.
11.- PAPADOPOULUS N G, ARAKAWA H, CARLSEN
K H, CUSTOVIC A, GERN J, LEMANSKE R, et al.
International consensus on pediatric asthma. Allergy
2012; 67: 976-97.
12.- BUSH A. Diagnosis of asthma in children under five.
Prim Care Respir J 2007; 16: 7-15.
13.- BEYDON N, DAVIS S D, LOMBARDI E, ALLEN J
L, ARETS H G, AURORA P, et al. An Official Ame-
rican Thoracic Society/European Respiratory Society
Statement: Pulmonary Function Testing in Preschool
Children. Am J Respir Crit Care Med 2007; 175: 1304-
45.
14.- ROSENFELD M, ALLEN J, ARETS B H, AURORA
P, BEYDON N, CALOGERO C, et al. An Official
American Thoracic Society Workshop Report: Optimal
Lung Function Tests for Monitoring Cystic Fibrosis,
Bronchopulmonary Dysplasia and Recurrent Wheezing
in Children Less Than 6 years of age. Ann Am Thorac
Soc 2013; 10: S1-S11.
15.- KADITIS A G, WINNIE G, SYROGIANNOPULOS
GA. Anti-Inflammatory Pharmacotherapy for Wheezing
in Preschool Children. Pediatr Pulmonol 2007; 42: 407-
20.
16.- CASTRO-RODRÍGUEZ J A, RODRIGO G. Efficacy of
inhaled corticosteroids in infants and preschoolers with
recurrent wheezing and asthma: a systematic review
with meta-analysis. Pediatrics 2009; 123: e519-e525.
17.- GUILBERT T, MORGAN W J, ZEIGER R S, MAU-
GER D T, BOEHMER S J, SZEFLER S J, et al. Long-
Term Inhaled Corticosteroids in Preschool Children at
High Risk for Asthma. N Engl J Med 2006; 354: 1985-
97.
18.- BACHARIER L, GUILBERT T, ZEIGER R, STRUNK
R, MORGAN W, LEMANSKE R, et al. Patient cha-
racteristics associated with improved outcomes with
use of an inhaled corticosteroid in preschool children
at risk for asthma. J Allergy Clin Immunol 2009; 123:
1077-82.
A. M. Herrera G. et al.
Rev Chil Enf Respir 2014; 30: 81-90